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RAR-Related Orphan Receptor C (RORC) (N-Term) Peptide

RORC Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN2183415
  • Target See all RORC products
    RORC (RAR-Related Orphan Receptor C (RORC))
    Protein Region
    N-Term
    Origin
    Human
    Source
    • 10
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    MDRAPQRQHR ASRELLAAKK THTSQIEVIP CKICGDKSSG IHYGVITCEG
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-RORC Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeat freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    RORC (RAR-Related Orphan Receptor C (RORC))
    Synonyms
    NR1F3 Peptide, RORG Peptide, RZR-GAMMA Peptide, RZRG Peptide, TOR Peptide, Nr1f3 Peptide, RORgamma Peptide, Thor Peptide, RAR related orphan receptor C Peptide, RAR-related orphan receptor C Peptide, RAR-related orphan receptor gamma Peptide, RORC Peptide, Rorc Peptide
    Background
    RORC encodes a protein which is a DNA-binding transcription factor and is a member of the NR1 subfamily of nuclear hormone receptors. The specific functions of this protein are not known, however, studies of a similar gene in mice have shown that RORC may be essential for lymphoid organogenesis and may play an important regulatory role in thymopoiesis. In addition, studies in mice suggest that the protein encoded by this gene may inhibit the expression of Fas ligand and IL2.

    Alias Symbols: NR1F3, RORG, RZR-GAMMA, RZRG, TOR

    Protein Size: 518
    Molecular Weight
    58 kDa
    Gene ID
    6097
    NCBI Accession
    NM_005060, NP_005051
    UniProt
    Q6I9R9
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