Replication Protein A2, 32kDa (RPA2) (C-Term) Peptide
RPA2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5513534
$160.46
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100 μg
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Quick Overview for Replication Protein A2, 32kDa (RPA2) (C-Term) Peptide (ABIN5513534)
Target
RPA2
(Replication Protein A2, 32kDa (RPA2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- SLVAFKIMPL EDMNEFTTHI LEVINAHMVL SKANSQPSAG RAPISNPGMS
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-RPA2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RPA2 (Replication Protein A2, 32kDa (RPA2))
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Background
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RPA2 functions as component of the alternative replication protein A complex (aRPA). aRPA binds single-stranded DNA and probably plays a role in DNA repair, it does not support chromosomal DNA replication and cell cycle progression through S- phase. In vitro, aRPA cannot promote efficient priming by DNA polymerase alpha but supports DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange. FUNCTION: Required for DNA recombination, repair and replication. The activity of RP-A is mediated by single-stranded DNA binding and protein interactions. Required for the efficient recruitment of the DNA double-strand break repair factor RAD51 to chromatin in response to DNA damage.
Alias Symbols: RPA2,REPA2,RPA32,RPA34,
Protein Size: 358 -
Gene ID
- 6118
Target
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