RE1-Silencing Transcription Factor (REST) (N-Term) Peptide
REST
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5514359
Quick Overview for RE1-Silencing Transcription Factor (REST) (N-Term) Peptide (ABIN5514359)
Target
REST
(RE1-Silencing Transcription Factor (REST))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- SGSSTAEEGD FSKGPIRCDR CGYNTNRYDH YTAHLKHHTR AGDNERVYKC
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-REST Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- REST (RE1-Silencing Transcription Factor (REST))
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Background
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This gene encodes a transcriptional repressor that represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described.
Alias Symbols: REST,NRSF, XBR,
Protein Size: 1097 -
Gene ID
- 5978
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NCBI Accession
- NP_005603
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UniProt
- Q13127
Target
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