RE1-Silencing Transcription Factor (REST) (Middle Region) Peptide
REST
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all REST products
- REST (RE1-Silencing Transcription Factor (REST))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-REST antibody (Catalog #: ARP32478_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- REST (RE1-Silencing Transcription Factor (REST))
- Synonyms
- NRSF Peptide, XBR Peptide, 2610008J04Rik Peptide, AA407358 Peptide, xbr Peptide, nrsf Peptide, rest Peptide, resta Peptide, REST Peptide, RE1 silencing transcription factor Peptide, RE1-silencing transcription factor Peptide, RE1-silencing transcription factor S homeolog Peptide, REST Peptide, Rest Peptide, rest.S Peptide, rest Peptide, LOC615792 Peptide
- Background
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REST is a transcriptional repressor which represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells, and it is thought that this repressor may act as a master negative regular of neurogenesis.This gene encodes a transcriptional repressor which represses neuronal genes in non-neuronal tissues. It is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells, and it is thought that this repressor may act as a master negative regular of neurogenesis. Alternatively spliced transcript variants have been described, however, their full length nature has not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: NRSF, XBR
Protein Interaction Partner: CTDSP1,EHMT2,GRM2,STMN2,HTT,RCOR1,SIN3B,HDAC1,HDAC2,Hdac1,KDM5C,NCOR1,RCOR1,RNF2,Sin3a,Sin3b
Protein Size: 1097 - Molecular Weight
- 122 kDa
- Gene ID
- 5978
- NCBI Accession
- NM_005612, NP_005603
- UniProt
- Q13127
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