Ganglioside-Induced Differentiation-Associated Protein 1-Like 1 (GDAP1L1) (Middle Region) Peptide
Quick Overview for Ganglioside-Induced Differentiation-Associated Protein 1-Like 1 (GDAP1L1) (Middle Region) Peptide (ABIN5518391)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Sequence
- ELWLCGCAFT LADVLLGATL HRLKFLGLSK KYWEDGSRPN LQSFFERVQR
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GDAP1L1 (Ganglioside-Induced Differentiation-Associated Protein 1-Like 1 (GDAP1L1))
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Background
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The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein. Several transcript variants encoding different isoforms, as well as a noncoding transcript variant, have been found for this gene.
Alias Symbols: dJ881L22.1, dJ995J12.1.1
Protein Size: 557 -
Gene ID
- 78997
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NCBI Accession
- NM_001256737, NP_001243666
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UniProt
- Q96MZ0
Target
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