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Ganglioside-Induced Differentiation-Associated Protein 1-Like 1 (GDAP1L1) Peptide

GDAP1L1 Reactivity: Human Host: Synthetic WB, BP
Catalog No. ABIN977349
$160.46
Plus shipping costs $50.00
100 μg
Shipping to: United States
Delivery in 11 to 17 Business Days

Quick Overview for Ganglioside-Induced Differentiation-Associated Protein 1-Like 1 (GDAP1L1) Peptide (ABIN977349)

Target

GDAP1L1 (Ganglioside-Induced Differentiation-Associated Protein 1-Like 1 (GDAP1L1))

Origin

Human

Source

  • 3
Synthetic

Application

Western Blotting (WB), Blocking Peptide (BP)
  • Characteristics

    This is a synthetic peptide designed for use in combination with anti-GDAP1L1 antibody (Catalog #: ARP49791_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    Purification

    Purified
  • Application Notes

    Each Investigator should determine their own optimal working dilution for specific applications.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    Concentration

    1 mg/mL

    Buffer

    Final peptide concentration is 1 mg/mL in PBS.

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C

    Storage Comment

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target

    GDAP1L1 (Ganglioside-Induced Differentiation-Associated Protein 1-Like 1 (GDAP1L1))

    Background

    The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. GDAP1L1 is similar in sequence to the human GDAP1 protein.The ganglioside GD3 synthase causes cell differentiation with neurite sprouting when transfected into the mouse neuroblastoma cell line Neuro2a. After differentiation, the expression of several genes is upregulated, including one that encodes a protein termed ganglioside-induced differentiation-associated protein 1 (Gdap1). A similar gene was found in humans, and mutations in the human gene are associated with Charcot-Marie-Tooth type 4A disease. The protein encoded by this gene is similar in sequence to the human GDAP1 protein.

    Alias Symbols: DKFZp761K228, dJ881L22.1, dJ995J12.1.1

    Protein Size: 367

    Molecular Weight

    42 kDa

    Gene ID

    78997

    NCBI Accession

    NM_024034, NP_076939

    UniProt

    Q96MZ0
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