Cell Death-Inducing DFFA-Like Effector A (CIDEA) (Middle Region) Peptide
CIDEA
Reactivity: Human
Host: Synthetic
WB
Catalog No. ABIN5518475
Quick Overview for Cell Death-Inducing DFFA-Like Effector A (CIDEA) (Middle Region) Peptide (ABIN5518475)
Target
CIDEA
(Cell Death-Inducing DFFA-Like Effector A (CIDEA))
Origin
Human
Source
Synthetic
Application
Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- RPFRVSNHDR SSRRGVMASS LQELISKTLD ALVIATGLVT LVLEEDGTVV
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CIDEA (Cell Death-Inducing DFFA-Like Effector A (CIDEA))
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Background
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This gene encodes the homolog of the mouse protein Cidea that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice that lack functional Cidea have higher metabolic rates, higher lipolysis in brown adipose tissue and higher core body temperatures when subjected to cold. These mice are also resistant to diet-induced obesity and diabetes. This suggests that in mice this gene product plays a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
Alias Symbols: CIDE-A,
Protein Size: 219 -
Gene ID
- 1149
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NCBI Accession
- NM_001279, NP_001270
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UniProt
- O60543
Target
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