Hemoglobin A-2 Peptide
Quick Overview for Hemoglobin A-2 Peptide (ABIN5624564)
Target
Source
Application
-
-
Peptide Type
- Synthetic
-
Supplier Product No.
- 000-001-gs8
-
Supplier
- Rockland
-
Purpose
- HbA-2 Control Peptide
-
Characteristics
- HbA-2 Control Peptide, Hemoglobin Subunit Delta, Hemoglobin Delta Chain 4, Delta-Globin 4, HbD, Sickle Cell Disease (SCD)
-
Purification
- Greater than 95% specific peptide
-
Purity
- Greater than 95% specific peptide
-
-
-
Application Notes
- Optional[Flow Cytometry Dilution]: HbA-2 peptide can be used as a control with the HbA-2 antibody. Control peptide should be used at 1.0 μg per 1.0 μL of antiserum in per assay.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
-
Reconstitution Buffer: Restore with deionized water (or equivalent)
Reconstitution Volume: 50μL
-
Concentration
- 1.0 mg/mL
-
Buffer
-
Buffer: None
Stabilizer: None
Preservative: None -
Preservative
- Without preservative
-
Storage
- 4 °C,-20 °C
-
Storage Comment
- Store vial at 2-8 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.
-
Expiry Date
- 6 months
-
-
- Hemoglobin A-2
-
Background
-
Synonyms: HbA-2 Control Peptide, Hemoglobin Subunit Delta, Hemoglobin Delta Chain 4, Delta-Globin 4, HbD, Sickle Cell Disease (SCD)
Background: HbA-2 or HbD peptide corresponds the delta-subunit specific sequence in the hemoglobin delta-subunit found in HbA-2. Functional hemoglobin (Hb) is a hetero tetramer and the dominant form of Adult Hb is composed of 2 alpha and 2 beta subunits (α2β2). Hemoglobin A-2 (HbA-2) is a normal but minor variant of hemoglobin A that consists of two alpha and two delta chains (α2δ2). Hemoglobin A-2 may be increased in beta thalassemia or in people who are heterozygous for the beta thalassemia gene, and HbA2 is also linked to neurological disorders. HbA-2 form exists in small amounts in all adult humans (1.5-3.1 % of all hemoglobin molecules) and is increased in people with Sickle-cell disease. Its normal biological role is not well understood. HbD peptide is suitable for use as a control with HbA-2 antibody. This peptide is ideal for investigators involved in Cardiovascular and developmental biology research.
-
Gene ID
- 3045
-
NCBI Accession
- NP_000510
-
UniProt
- P02042
Target
-
