Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) (N-Term) Peptide
Quick Overview for Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) (N-Term) Peptide (ABIN5624608)
Target
Source
Application
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Peptide Type
- Synthetic
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Protein Region
- N-Term
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Supplier Product No.
- 000-001-gn7
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Supplier
- Rockland
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Purpose
- MEK1 N-Term Blocking Peptide
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Characteristics
- MAP2K, MEK, MEK1, MKK1, PRKMK1, MEK-1 Blocking peptide, MEK-1 Control peptide
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Purification
- Purity was determined to be greater than 95% specific peptide by analysis by HPLC and by reducing and non-reducing SDS-PAGE.
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Purity
- Greater than 95% specific peptide by analysis by HPLC and by reducing and non-reducing SDS-PAGE.
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Application Notes
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Application Note: MEK1 N-term blocking peptide is suitable as a control for polyclonal or monoclonal Anti-MEK1 in immunological assays.
Western Blot Dilution: 50 ng
Other: Dot Blot
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
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Reconstitution Buffer: Restore with deionized water (or equivalent)
Reconstitution Volume: 50μL
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Concentration
- 1.0 mg/mL
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Buffer
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Buffer: None
Stabilizer: None
Preservative: 0.01 % (w/v) Sodium Azide -
Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store vial at 2-8 °C prior to opening. Aliquot contents and freeze at -20 °C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.
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Expiry Date
- 6 months
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- MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
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Background
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Synonyms: MAP2K, MEK, MEK1, MKK1, PRKMK1, MEK-1 Blocking peptide, MEK-1 Control peptide
Background: Mitogen-activated protein kinase kinase 1, also known as MKK or MEK, is an integral component of the MAP kinase cascade that regulates cell growth and differentiation. This pathway also plays a key role in synaptic plasticity in the brain. Activated MEK 1 acts as a dual specificity kinase phosphorylating both a threonine and a tyrosine residue on MAP kinase. MEK1 and MEK2 are about 80 % identical to each other, and nearly identical within the kinase domain. MEK1 is ideal for investigators involved in Neuroscience, Cell Signaling and Cancer Research.
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UniProt
- Q02750
Target
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