V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1) (N-Term) Peptide
AKT1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all AKT1 products
- AKT1 (V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RGEYIKTWRP RYFLLKNDGT FIGYKERPQD VDQREAPLNN FSVAQCQLMK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- AKT1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- AKT1 (V-Akt Murine Thymoma Viral Oncogene Homolog 1 (AKT1))
- Synonyms
- AKT Peptide, CWS6 Peptide, PKB Peptide, PKB-ALPHA Peptide, PRKBA Peptide, RAC Peptide, RAC-ALPHA Peptide, Akt Peptide, Rac Peptide, PKB/Akt Peptide, PKBalpha Peptide, AKT/PKB Peptide, AKT1 Peptide, Akt/PKB Peptide, Akt1 Peptide, CG4006 Peptide, D-Akt Peptide, DAKT1 Peptide, DAKT1/PKB Peptide, DAkt Peptide, DAkt1 Peptide, DPKB Peptide, DRAC-PK Peptide, DRAC-PK66 Peptide, DRAC-PK85 Peptide, Dakt Peptide, Dakt1 Peptide, Dmel\\CG4006 Peptide, Dpkb Peptide, PKB/AKT Peptide, PKB/dAKT Peptide, RacPK Peptide, akt Peptide, akt1 Peptide, dAKT Peptide, dAKT/dPKB Peptide, dAKT1 Peptide, dAkt Peptide, dAkt/PKB Peptide, dAkt1 Peptide, dPKB Peptide, dakt Peptide, dakt1 Peptide, l(3)04226 Peptide, l(3)89Bq Peptide, p-Akt Peptide, pAkt Peptide, ACT-5 Peptide, akt-1 Peptide, pkb Peptide, v-akt Peptide, v-akt1 Peptide, xAct Peptide, ATAKT1 Peptide, F18A8.2 Peptide, F18A8_2 Peptide, K+ transporter 1 Peptide, POTASSIUM TRANSPORTER Peptide, AKT serine/threonine kinase 1 Peptide, thymoma viral proto-oncogene 1 Peptide, CG4006 gene product from transcript CG4006-RE Peptide, actin beta Peptide, v-akt murine thymoma viral oncogene homolog 1 S homeolog Peptide, v-akt murine thymoma viral oncogene homolog 1 Peptide, K+ transporter 1 Peptide, Serine/threonine-protein kinase akt-1 Peptide, AKT1 Peptide, Akt1 Peptide, ACTB Peptide, akt1.S Peptide, akt1 Peptide, KT1 Peptide, akt-1 Peptide
- Background
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The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene.
Alias Symbols: AKT, PKB, RAC, CWS6, PRKBA, PKB-ALPHA, RAC-ALPHA
Protein Size: 480 - Gene ID
- 207
- NCBI Accession
- NM_001014431, NP_001014431
- UniProt
- P31749
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