rho GTPase Activating Protein 26 (ARHGAP26) (Middle Region) Peptide
ARHGAP26
Reactivity: Human
Host: Synthetic
WB
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- Target See all GRAF (ARHGAP26) products
- GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Western Blotting (WB)
- Sequence
- LWMEAMDGRE PVYNSNKDSQ SEGTAQLDSI GFSIIRKCIH AVETRGINEQ
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RHG26 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- GRAF (ARHGAP26) (rho GTPase Activating Protein 26 (ARHGAP26))
- Synonyms
- ARHGAP26 Peptide, GRAF Peptide, GRAF1 Peptide, OPHN1L Peptide, OPHN1L1 Peptide, 1810044B20Rik Peptide, 2610010G17Rik Peptide, 4933432P15Rik Peptide, AI853435 Peptide, mKIAA0621 Peptide, Rho GTPase activating protein 26 Peptide, ARHGAP26 Peptide, Arhgap26 Peptide
- Background
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Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ARHGAP26,GRAF,KIAA0621,OPHN1L,
Protein Size: 814 - Gene ID
- 23092
- NCBI Accession
- NP_055886
- UniProt
- Q9UNA1
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