Epidermal Growth Factor Receptor (EGFR) (C-Term) Peptide
EGFR
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5671562
Quick Overview for Epidermal Growth Factor Receptor (EGFR) (C-Term) Peptide (ABIN5671562)
Target
EGFR
(Epidermal Growth Factor Receptor (EGFR))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- LNPAPSRDPH YQDPHSTAVG NPEYLNTVQP TCVNSTFDSP AHWAQKGSHQ
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- EGFR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- EGFR (Epidermal Growth Factor Receptor (EGFR))
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Background
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The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer.
Alias Symbols: ERBB, HER1, mENA, ERBB1, PIG61, NISBD2
Protein Size: 1210 -
Gene ID
- 1956
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NCBI Accession
- NM_005228, NP_005219
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UniProt
- P00533
Target
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