HNF1 Homeobox B (HNF1B) (N-Term) Peptide
HNF1B
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all HNF1B products
- HNF1B (HNF1 Homeobox B (HNF1B))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- AKGRLSGDEG SEDGDDYDTP PILKELQALN TEEAAEQRAE VDRMLSEDPW
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- HNF1B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HNF1B (HNF1 Homeobox B (HNF1B))
- Background
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This gene encodes a member of the homeodomain-containing superfamily of transcription factors. The protein binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin-dependent diabetes mellitus, and expression of this gene is altered in some types of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: FJHN, HNF2, LFB3, TCF2, HPC11, LF-B3, MODY5, TCF-2, VHNF1, HNF-1B, HNF1beta, HNF-1-beta
Protein Size: 427 - Gene ID
- 6928
- NCBI Accession
- NM_000458, NP_000449
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