HNF1 Homeobox B (HNF1B) Peptide
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- Target See all HNF1B products
- HNF1B (HNF1 Homeobox B (HNF1B))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TCF2 antibody (Catalog #: ARP32320_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- HNF1B (HNF1 Homeobox B (HNF1B))
- Synonyms
- FJHN Peptide, HNF-1B Peptide, HNF1beta Peptide, HNF2 Peptide, HPC11 Peptide, LF-B3 Peptide, LFB3 Peptide, MODY5 Peptide, TCF-2 Peptide, TCF2 Peptide, VHNF1 Peptide, HNF-1b Peptide, HNF1B Peptide, AI385728 Peptide, AI987804 Peptide, HNF-1Beta Peptide, Hnf1beta Peptide, Tcf-2 Peptide, Tcf2 Peptide, vHNF1 Peptide, vHNF-1 Peptide, chunp6877 Peptide, hnf1b Peptide, mst Peptide, tcf2 Peptide, vhnf1 Peptide, lfb3 Peptide, hnf-1beta Peptide, hnf1-beta Peptide, hnf1beta Peptide, HNF1g Peptide, wu:fc23f06 Peptide, HNF1 homeobox B Peptide, HNF1 homeobox Ba Peptide, HNF1 homeobox B S homeolog Peptide, HNF1 homeobox B L homeolog Peptide, HNF1 homeobox Bb Peptide, HNF1B Peptide, Hnf1b Peptide, hnf1ba Peptide, hnf1b.S Peptide, hnf1b.L Peptide, hnf1bb Peptide
- Background
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TCF2 encodes transcription factor 2, a liver-specific factor of the homeobox-containing basic helix-turn-helix family. The TCF2 protein is believed to form heterodimers with another liver-specific member of this transcription factor family, TCF1, depending on the TCF2 isoform, the result may be to activate or inhibit transcription of target genes. Mutation of TCF2 that disrupts normal function has been identified as the cause of MODY5 (Maturity-Onset of Diabetes, Type 5).
Alias Symbols: FJHN, HNF1beta, HNF2, LFB3, MODY5, TCF2, VHNF1, HPC11, LF-B3
Protein Interaction Partner: ATF1,CREBBP,HNF1A,ATF1,CREB1,HNF1A
Protein Size: 399 - Molecular Weight
- 45 kDa
- Gene ID
- 6928
- NCBI Accession
- NM_006481, NP_006472
- UniProt
- P35680
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