Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (C-Term) Peptide
RRM2B
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5671856
$160.46
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100 μg
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Quick Overview for Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (C-Term) Peptide (ABIN5671856)
Target
RRM2B
(Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Sequence
- IEFVADRLLV ELGFSKVFQA ENPFDFMENI SLEGKTNFFE KRVSEYQRFA
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- RRM2B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
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Background
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This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.
Alias Symbols: P53R2, MTDPS8A, MTDPS8B
Protein Size: 299 -
Gene ID
- 50484
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NCBI Accession
- NM_001172477, NP_001165948
Target
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