Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B) (Middle Region) Peptide
RRM2B
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RRM2B products
- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- VHSEMYSLLI DTYIRDPKKR EFLFNAIETM PYVKKKADWA LRWIADRKST
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RRM2B Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RRM2B (Ribonucleotide Reductase M2 B (TP53 Inducible) (RRM2B))
- Synonyms
- p53r2 Peptide, RRM2B Peptide, MTDPS8A Peptide, MTDPS8B Peptide, P53R2 Peptide, p53R2 Peptide, ribonucleotide reductase M2 B (TP53 inducible) S homeolog Peptide, ribonucleotide reductase regulatory TP53 inducible subunit M2B Peptide, ribonucleotide reductase M2 B (TP53 inducible) Peptide, rrm2b.S Peptide, RRM2B Peptide, rrm2b Peptide, Rrm2b Peptide
- Background
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This gene encodes the small subunit of a p53-inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in this gene have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia-5, and mitochondrial neurogastrointestinal encephalopathy. Alternatively spliced transcript variants have been described.
Protein Size: 299 - Gene ID
- 50484
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