Ribonucleotide Reductase M2 (RRM2) (C-Term) Peptide
Quick Overview for Ribonucleotide Reductase M2 (RRM2) (C-Term) Peptide (ABIN5672273)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- QYIEFVADRL MLELGFSKVF RVENPFDFME NISLEGKTNF FEKRVGEYQR
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- RRM2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RRM2 (Ribonucleotide Reductase M2 (RRM2))
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Background
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This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X.
Alias Symbols: R2, RR2, RR2M
Protein Size: 389 -
Gene ID
- 6241
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NCBI Accession
- NM_001034, NP_001025
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UniProt
- P31350
Target
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