Ribonucleotide Reductase M2 (RRM2) (N-Term) Peptide
RRM2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all RRM2 products
- RRM2 (Ribonucleotide Reductase M2 (RRM2))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RRM2 antibody (Catalog #: ARP46031_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- RRM2 (Ribonucleotide Reductase M2 (RRM2))
- Synonyms
- R2 Peptide, RR2 Peptide, RR2M Peptide, AA407299 Peptide, rrm2 Peptide, rr2m Peptide, cb111 Peptide, chunp6884 Peptide, r2 Peptide, ribonucleotide reductase regulatory subunit M2 Peptide, ribonucleotide reductase M2 Peptide, ribonucleotide reductase M2, gene 2 L homeolog Peptide, ribonucleotide reductase M2, gene 1 Peptide, ribonucleotide reductase M2 polypeptide Peptide, RRM2 Peptide, Rrm2 Peptide, rrm2.2.L Peptide, rrm2.1 Peptide, rrm2 Peptide
- Background
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RRM2 provides the precursors necessary for DNA synthesis. RRM2 catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. RRM2 inhibits Wnt signaling.Ribonucleotide reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. It is composed of 2 non-identical subunits, proteins M1 and M2. Synthesis of M2 is regulated in a cell-cycle dependent fashion. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: R2, RR2M, RR2
Protein Interaction Partner: CDH1,CDK1,RRM1,RRM2B,TP53,RRM1,TP53
Protein Size: 389 - Molecular Weight
- 45 kDa
- Gene ID
- 6241
- NCBI Accession
- NM_001034, NP_001025
- UniProt
- P31350
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