Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) (N-Term) Peptide
KCNIP3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5672492
Quick Overview for Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) (N-Term) Peptide (ABIN5672492)
Target
DREAM (KCNIP3)
(Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- LLGDLGHTPL SKKEGIKWQR PRLSRQALMR CCLVKWILSS TAPQGSDSSD
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- KCNIP3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
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Background
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This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: CSEN, DREAM, KCHIP3
Protein Size: 256 -
Gene ID
- 30818
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NCBI Accession
- NM_001034914, NP_001030086
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UniProt
- Q9Y2W7
Target
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