Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) Peptide
KCNIP3
Reactivity: Human
Host: Synthetic
BP, WB, IHC
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- Target See all DREAM (KCNIP3) products
- DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CSEN antibody (Catalog #: ARP31932_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
- Synonyms
- CSEN Peptide, DREAM Peptide, KCHIP3 Peptide, 4933407H12Rik Peptide, AI413860 Peptide, Csen Peptide, KChIP3 Peptide, R74849 Peptide, Dream Peptide, rKChIP3 Peptide, csen Peptide, im:7145308 Peptide, kcnip3 Peptide, zgc:73306 Peptide, KCNIP3 Peptide, potassium voltage-gated channel interacting protein 3 Peptide, Kv channel-interacting protein 4 Peptide, calsenilin Peptide, Kv channel interacting protein 3, calsenilin Peptide, Kv channel interacting protein 3b, calsenilin Peptide, KCNIP3 Peptide, LOC5568664 Peptide, CpipJ_CPIJ002549 Peptide, Tsp_05009 Peptide, Kcnip3 Peptide, kcnip3b Peptide, kcnip3 Peptide
- Background
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CSEN is a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The protein encoded by this gene is also shown to function as a calcium-regulated transcriptional repressor, and to interact with presenilins. Mutations in the presenilin genes have been implicated in Alzheimer's disease.
Alias Symbols: CSEN, DREAM, KCHIP3
Protein Interaction Partner: CASP3,CD177,CREB1,CREM,PSEN1,PSEN2,CD177,CREB1,CREM,CRK,PSEN1,PSEN2
Protein Size: 256 - Molecular Weight
- 29 kDa
- Gene ID
- 30818
- NCBI Accession
- NM_013434, NP_038462
- UniProt
- Q9Y2W7
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