Angiotensin I Converting Enzyme 2 (ACE2) (C-Term) Peptide
ACE2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ACE2 products
- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PNQPPVSIWL IVFGVVMGVI VVGIVILIFT GIRDRKKKNK ARSGENPYAS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- ACE2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
- Synonyms
- ACE1 Peptide, CD143 Peptide, DCP Peptide, DCP1 Peptide, ICH Peptide, MVCD3 Peptide, ACEH Peptide, 2010305L05Rik Peptide, zgc:92514 Peptide, angiotensin I converting enzyme Peptide, angiotensin I converting enzyme 2 Peptide, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 Peptide, ACE Peptide, ACE2 Peptide, Ace2 Peptide, ace2 Peptide
- Background
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The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. The organ- and cell-specific expression of this gene suggests that it may play a role in the regulation of cardiovascular and renal function, as well as fertility. In addition, the encoded protein is a functional receptor for the spike glycoprotein of the human coronaviruses SARS and HCoV-NL63.
Alias Symbols: ACEH
Protein Size: 805 - Gene ID
- 59272
- NCBI Accession
- NM_021804, NP_068576
- UniProt
- Q9BYF1
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