beta-Site APP-Cleaving Enzyme 2 (BACE2) (Middle Region) Peptide
BACE2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5672853
Quick Overview for beta-Site APP-Cleaving Enzyme 2 (BACE2) (Middle Region) Peptide (ABIN5672853)
Target
BACE2
(beta-Site APP-Cleaving Enzyme 2 (BACE2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- PAGAANFLAM VDNLQGDSGR GYYLEMLIGT PPQKLQILVD TGSSNFAVAG
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- BACE2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BACE2 (beta-Site APP-Cleaving Enzyme 2 (BACE2))
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Background
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This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.
Alias Symbols: ASP1, BAE2, DRAP, AEPLC, ALP56, ASP21, CDA13, CEAP1
Protein Size: 468 -
Gene ID
- 25825
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NCBI Accession
- NM_012105, NP_036237
Target
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