PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (Middle Region) Peptide
PINX1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PINX1 products
- PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LGLGATINNE DNWIAHQDDF NQLLAELNTC HGQETTDSSD KKEKKSFSLE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- PINX1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) peptide
PINX1 Reactivity: Human, Mouse, Rat, Cow, Dog, Pig Host: Synthetic BP, Imm
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
- Background
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Binds to and activates the CDH5 promoter, hence plays a role in the transcriptional regulation of genes expressed in the hemogenic endothelium and blocks further differentiation into blood precursors. May be required for the survival of both hematopoietic and endothelial precursors during specification. Competes with GATA4 for binding and activation of the FGF3 promoter. Represses Wnt/beta-catenin-stimulated transcription, probably by targeting CTNNB1 to proteasomal degradation. Binds the DNA sequence 5'-AACAAT-3'.
Alias Symbols: Gno1, LPTL, LPTS, Pxr1
Protein Size: 440 - Gene ID
- 54984
- NCBI Accession
- NM_001284356, NP_001271285
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