PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) (Middle Region) Peptide
PINX1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PINX1 products
- PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EKKSFSLEEK SKISKNRVHY MKFTKGKDLS SRSKTDLDCI FGKRQSKKTP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-PINX1 Antibody(ARP57058_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1) peptide
PINX1 Reactivity: Human, Mouse, Rat, Cow, Dog, Pig Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PINX1 (PIN2/TERF1 Interacting, Telomerase Inhibitor 1 (PINX1))
- Synonyms
- PINX1 Peptide, LPTL Peptide, LPTS Peptide, 2210403I16Rik Peptide, 2610028A01Rik Peptide, 67-11-3 Peptide, AU024023 Peptide, LPTS1 Peptide, RGD1566025 Peptide, PIN2/TERF1 interacting telomerase inhibitor 1 Peptide, PIN2/TERF1 interacting, telomerase inhibitor 1 Peptide, PINX1 Peptide, Pinx1 Peptide
- Background
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PINX1 is a microtubule-binding protein essential for faithful chromosome segregation. PINX1 mediates TRF1 and TERT accumulation in nucleolus and enhances TRF1 binding to telomeres. PINX1 inhibits telomerase activity and may inhibit cell proliferation and act as tumor suppressor.
Alias Symbols: FLJ20565, LPTL, LPTS, MGC8850
Protein Interaction Partner: MCRS1,MPZ,PAFAH1B2,TERF1,TERT,AHCY,CALM3,CAPRIN1,GTPBP4,HRNR,MCRS1,PABPC1,PABPC4,PAFAH1B2,PLEKHJ1,RPL23A,RPL31,RPS10,RPS16,RPS19,RPS28,RPS3A,TERF1,TERT,TXN
Protein Size: 328 - Molecular Weight
- 37 kDa
- Gene ID
- 54984
- NCBI Accession
- NM_017884, NP_060354
- UniProt
- Q96BK5
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