phospholipid Scramblase 3 (PLSCR3) (N-Term) Peptide
PLSCR3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all PLSCR3 products
- PLSCR3 (phospholipid Scramblase 3 (PLSCR3))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PPKGYAPSPP PPYPVTPGYP EPALHPGPGQ APVPAQVPAP APGFALFPSP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- PLSCR3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PLSCR3 (phospholipid Scramblase 3 (PLSCR3))
- Synonyms
- 2210403O21Rik Peptide, 2610037N06Rik Peptide, ESTM3 Peptide, X83310 Peptide, Pls3 Peptide, zgc:77051 Peptide, phospholipid scramblase 3 Peptide, phospholipid scramblase 3b Peptide, PLSCR3 Peptide, Plscr3 Peptide, plscr3b Peptide
- Background
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May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.
Protein Size: 295 - Gene ID
- 57048
- NCBI Accession
- NM_001201576, NP_001188505
- UniProt
- Q9NRY6
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