phospholipid Scramblase 3 (PLSCR3) (N-Term) Peptide
PLSCR3
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5673451
Quick Overview for phospholipid Scramblase 3 (PLSCR3) (N-Term) Peptide (ABIN5673451)
Target
PLSCR3
(phospholipid Scramblase 3 (PLSCR3))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- N-Term
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Sequence
- GYLPPKGYAP SPPPPYPVTP GYPEPALHPG PGQAPVPAQV PAPAPGFALF
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- PLSCR3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PLSCR3 (phospholipid Scramblase 3 (PLSCR3))
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Background
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May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system. Seems to play a role in apoptosis, through translocation of cardiolipin from the inner to the outer mitochondrial membrane which promotes BID recruitment and enhances tBid-induced mitochondrial damages.
Protein Size: 295 -
Gene ID
- 57048
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NCBI Accession
- NM_001201576, NP_001188505
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UniProt
- Q9NRY6
Target
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