tRNA-Histidine Guanylyltransferase 1-Like (THG1L) (Middle Region) Peptide
THG1L
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all THG1L products
- THG1L (tRNA-Histidine Guanylyltransferase 1-Like (THG1L))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DGRVVVYPSN QTLKDYLSWR QADCHINNLY NTVFWALIQQ SGLTPVQAQG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- THG1L Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- THG1L (tRNA-Histidine Guanylyltransferase 1-Like (THG1L))
- Synonyms
- ICF45 Peptide, IHG-1 Peptide, 1700121M19Rik Peptide, 5730409G07Rik Peptide, AA387658 Peptide, tRNA-histidine guanylyltransferase 1 like Peptide, tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) Peptide, tRNA-histidine guanylyltransferase 1-like Peptide, THG1L Peptide, Thg1l Peptide
- Background
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The protein encoded by this gene is a mitochondrial protein that is induced by high levels of glucose and is associated with diabetic nephropathy. The encoded protein appears to increase mitochondrial biogenesis, which could lead to renal fibrosis. Another function of this protein is that of a guanyltransferase, adding GMP to the 5' end of tRNA(His). Several transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ICF45, IHG-1, hTHG1
Protein Size: 298 - Gene ID
- 54974
- NCBI Accession
- NM_017872, NP_060342
- UniProt
- Q9NWX6
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