Cathelicidin Antimicrobial Peptide (CAMP) (AA 14-34) Peptide
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- Target See all Cathelicidin (CAMP) products
- Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))
- Protein Region
- AA 14-34
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Source
- Synthetic
- Supplier Product No.
- 000-001-m37
- Supplier
- Rockland
- Purpose
- LL-37, (14-34) Peptide
- Purity
- Greater than 95% specific peptide.
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- Application Notes
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Other: Control peptide should be used at 1.0 μg per 1.0 μL of antiserum per assay.
Application_Note: LL-37, 14-34 Control Peptide is suitable for use in ELISA, Western Blot, Dot blot, PCA, and other assays. Control peptide should be used at 1.0 μg per 1.0 μL of antiserum in per assay. Specific conditions for reactivity should be optimized by the end user.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
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Reconstitution_Buffer: Restore with deionized water (or equivalent)
Reconstitution_Volume: 1.0 mL
- Concentration
- 1.0 mg/mL
- Storage
- 4 °C,-20 °C
- Storage Comment
- Store vial at 2 - 8 ° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.
- Expiry Date
- 12 months
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- Target
- Cathelicidin (CAMP) (Cathelicidin Antimicrobial Peptide (CAMP))
- Background
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Synonyms: Cathelicidin antimicrobial peptide, 18 kDa cationic antimicrobial protein, CAP-18, hCAP-18, Antibacterial protein FALL-39, FALL-39 peptide antibiotic, Antibacterial protein LL-37, CAMP, CAP18, FALL39, HSD26, control peptide, blocking peptide
Background: Cathelicidin (LL-37) are a family of antimicrobial proteins found in lysosomes of macrophages and polymorphonuclear leukocytes. Along with the family of proteins known as defensins, cathelicidins participate in the first line of defense by preventing local infection and systemic invasion of microbes. LL-37 binds to bacterial lipopolysaccharides (LPS) and is a potent chemotactic factor for recruiting mast cells to sites of inflammation. LL-37 is present in inflammatory skin diseases that include psoriasis, sub-acute lupus erthematosus, dermatitis and nickel contact hypersensitivity. It is not found in normal skin epidermis. The secreted protein is expressed primarily in bone marrow, testis and neutrophils.
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