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Parathyroid Hormone (PTH) (AA 7-34) Peptide

PTH Host: Synthetic Without preservative
Rockland
Catalog No. ABIN6699433
Supplier Product No.: 000-001-m32

Quick Overview for Parathyroid Hormone (PTH) (AA 7-34) Peptide (ABIN6699433)

Target

PTH (Parathyroid Hormone (PTH))

Source

  • 19
Synthetic
  • Protein Region

    AA 7-34

    Supplier Product No.

    000-001-m32

    Supplier

    Rockland

    Purpose

    Parathyroid hormone (pTH) Rat 7-34 peptide

    Purity

    Greater than 95% specific peptide.
  • Application Notes

    Other: Control peptide should be used at 1.0 μg per 1.0 μL of antiserum per assay.

    Application_Note: Parathyroid hormone (pTH) Rat 7-34 Control Peptide is suitable for use in ELISA, Western Blot, Dot blot, PCA, and other assays. Control peptide should be used at 1.0 μg per 1.0 μL of antiserum in per assay. Specific conditions for reactivity should be optimized by the end user.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Reconstitution_Buffer: Restore with deionized water (or equivalent)

    Reconstitution_Volume: 1.0 mL

    Concentration

    1.0 mg/mL

    Preservative

    Without preservative

    Storage

    4 °C,-20 °C

    Storage Comment

    Store vial at 2 - 8 ° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Dilute only prior to immediate use.

    Expiry Date

    12 months
  • Target

    PTH (Parathyroid Hormone (PTH))

    Background

    Synonyms: Parathyroid hormone, PTH, Parathormone, Parathyrin, control peptide, blocking peptide

    Background: Parathyroid hormone (pTH) is the most important endocrine regulator of Ca2+ and phosphorus concentration in the extracellular fluid. pTH is secreted from cells of the parathyroid glands and acts for the most part via the binding to specific G-protein coupled receptors on the surface of  target cells in bone and kidney, utilizing the second messenger adenylate cyclase to regulate cAMP levels in cells.  Like most other protein hormones, parathyroid hormone is synthesized as a preprohormone and is processed intracellularly.  The mature hormone, 84 amino acids in length, is released from secretory vesicles into the blood.  Biologic effects of large C-terminal parathyroid hormone (PTH) fragments, such as pTH 7-84, are thought to regulate PTH secretion via an autocrine/paracrine regulatory mechanism

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