omega-Conotoxin SVIB Peptide
Reactivity: Conus striatus (Striated cone)
Host: Synthetic
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Catalog No. ABIN7887404
$596.31
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Quick Overview for omega-Conotoxin SVIB Peptide (ABIN7887404)
Target
omega-Conotoxin SVIB
Origin
Conus striatus (Striated cone)
Source
Synthetic
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Peptide Type
- Synthetic
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Biological Activity
- Active
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Purpose
- ω-Conotoxin SVIB
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Sequence
- CKLKGQSCRK TSYDCCSGSC GRSGKC-NH2
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Specificity
- Toxin target: N-type (CaV2.2) and P/Q-type (CaV2.1) calcium channels
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Purity
- ≥98 % (HPLC)
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Biological Activity Comment
- ω-Conotoxin SVIB is a potent blocker of voltage-gated Ca2+ channels1.
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Application Notes
- Antigen Preadsorption Control: 10 - 50 nM
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom. The lyophilized product may be difficult to visualize. Add solvent directly to the centrifuged vial and dissolve by gently tapping, tilting, or rolling the vial. Avoid vigorous vortexing, a brief, light vortex of 1-2 seconds is acceptable if necessary. The product is readily soluble in high-quality pure water at micromolar to millimolar concentrations (typically 100 μM to 1 mM). For long-term storage in solution, we recommend preparing a stock solution by dissolving the product in double-distilled water (ddH2O) at a concentration between 100-1000x the final working concentration. Divide the stock solution into small, single-use aliquots and store at -20 °C. Before use, thaw the relevant vial(s) and dilute to the desired working concentration in your working buffer. Centrifuge all product preparations before use. It is recommended to prepare fresh working solutions just before use. Avoid multiple freeze-thaw cycles to maintain optimal biological activity.
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Buffer
- Lyophilized from double distilled water (ddH2O). May contain residual trifluoroacetate (TFA).
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Handling Advice
- Centrifuge the vial at 10,000 x g for 5 minutes before opening to ensure all material is collected at the bottom,Avoid multiple freeze-thaw cycles to maintain optimal biological activity,Avoid vigorous vortexing. protect from moisture
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Storage
- -20 °C
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Storage Comment
- The product is shipped as a lyophilized powder at room temperature. Upon receipt, store at -20°C and protect from moisture.
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- omega-Conotoxin SVIB
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Background
- A potent, reversible N-type (CaV2.2) and irreversible P/Q-type (CaV2.1) voltage-gated calcium channel blocker
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Molecular Weight
- 2739 Da
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UniProt
- P28881
Target
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