ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) Peptide
Quick Overview for ADAM Metallopeptidase Domain 17 (ADAM17) (C-Term) Peptide (ABIN8094027)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- ADAM17 Peptide - C-terminal region
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Sequence
- DGFEKDPFPN SSTAAKSFED LTDHPVTRSE KAASFKLQRQ NRVDSKETEC
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-ADAM17 Antibody (ARP61304_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
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Background
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Background Information: This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme, binds mitotic arrest deficient 2 protein, and also plays a prominent role in the activation of the Notch signaling pathway.
Alternative Symbols: ADAM17,CSVP,TACE,
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Molecular Weight
- 90kDa
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Gene ID
- 6868
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NCBI Accession
- NP_003174
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UniProt
- P78536
Target
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