ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) (Middle Region) Peptide
Quick Overview for ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1) (Middle Region) Peptide (ABIN8094214)
Target
Origin
Source
Application
-
-
Protein Region
- Middle Region
-
Purpose
- ARFGAP1 Peptide - middle region
-
Sequence
- GQPQSVTASS DKAFEDWLND DLGSYQGAQG NRYVGFGNTP PPQKKEDDFL
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Comment
-
This is a synthetic peptide designed for use in combination with anti-ARFGAP1 Antibody(ARP57149_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- ARFGAP1 (ADP-Ribosylation Factor GTPase Activating Protein 1 (ARFGAP1))
-
Background
-
Background Information: The protein encoded by this gene is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). The encoded protein promotes hydrolysis of ARF1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Two transcript variants encoding different isoforms have been found for this gene.
Alternative Symbols: ARF1GAP, HRIHFB2281, MGC39924
-
Molecular Weight
- 45kDa
-
Gene ID
- 55738
-
NCBI Accession
- NP_060679
-
UniProt
- Q8N6T3
Target
-
