ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3) (Middle Region) Peptide
Quick Overview for ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3) (Middle Region) Peptide (ABIN8094222)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- ARFGAP3 Peptide - middle region
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Sequence
- TSDMQTIEQE SPIMAKPRKK YNDDSDDSYF TSSSSYFDEP VELRSSSFSS
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ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3) peptide
ARFGAP3 Reactivity: Human, Mouse, Cow, Dog, Rat Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- ARFGAP3 Antibody (ARP82477_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- ARFGAP3 (ADP-Ribosylation Factor GTPase Activating Protein 3 (ARFGAP3))
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Background
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Background Information: The protein encoded by this gene is a GTPase-activating protein (GAP) that associates with the Golgi apparatus and regulates the early secretory pathway of proteins. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1 (ARF1)-bound GTP, which is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is a prerequisite for the fusion of these vesicles with target compartments. The activity of this protein is sensitive to phospholipids. Multiple transcript variants encoding different isoforms have been found for this gene. This gene was originally known as ARFGAP1, but that is now the name of a related but different gene.
Alternative Symbols: ARFGAP1
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Molecular Weight
- 51 kDa
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Gene ID
- 26286
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NCBI Accession
- NP_001135765
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UniProt
- Q9NP61
Target
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