Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (C-Term) Peptide
Quick Overview for Adrenergic, Beta, Receptor Kinase 1 (ADRBK1) (C-Term) Peptide (ABIN8094273)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- GRK2 Peptide - C-terminal region
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Sequence
- ILQCDSDPEL VQWKKELRDA YREAQQLVQR VPKMKNKPRS PVVELSKVPL
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-ADRBK1 Antibody(ARP51966_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- GRK2 (ADRBK1) (Adrenergic, Beta, Receptor Kinase 1 (ADRBK1))
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Background
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Background Information: This gene encodes a member of the G protein-coupled receptor kinase family of proteins. The encoded protein phosphorylates the beta-adrenergic receptor as well as a wide range of other substrates including non-GPCR cell surface receptors, and cytoskeletal, mitochondrial, and transcription factor proteins. Data from rodent models supports a role for this gene in embryonic development, heart function and metabolism. Elevated expression of this gene has been observed in human patients with heart failure and Alzheimer's disease.
Alternative Symbols: BARK1, ADRBK1, BETA-ARK1
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Molecular Weight
- 79kDa
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Gene ID
- 156
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NCBI Accession
- NP_001610
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UniProt
- P25098
Target
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