Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) (Middle Region) Peptide
Quick Overview for Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5) (Middle Region) Peptide (ABIN8094351)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- ADH5 Peptide - middle region
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Sequence
- KSVESVPKLV SEYMSKKIKV DEFVTHNLSF DEINKAFELM HSGKSIRTVV
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-ADH5 Antibody(ARP51767_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))
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Background
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Background Information: This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.
Alternative Symbols: ADH-3, ADHX, FDH, FALDH, GSNOR, GSH-FDH
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Molecular Weight
- 40kDa
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Gene ID
- 128
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NCBI Accession
- NP_000662
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UniProt
- P11766
Target
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