Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (Middle Region) Peptide
Quick Overview for Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (Middle Region) Peptide (ABIN8094356)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- ALDH1A1 Peptide - middle region
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Sequence
- SVERAKKYIL GNPLTPGVTQ GPQIDKEQYD KILDLIESGK KEGAKLECGG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-ALDH1A1 Antibody(ARP58737_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))
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Background
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Background Information: This protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. Two major liver isoforms of this enzyme, cytosolic and mitochondrial, can be distinguished by their electrophoretic mobilities, kinetic properties, and subcellular localizations. Most Caucasians have two major isozymes, while approximately 50 % of Orientals have only the cytosolic isozyme, missing the mitochondrial isozyme. A remarkably higher frequency of acute alcohol intoxication among Orientals than among Caucasians could be related to the absence of the mitochondrial isozyme. This gene encodes a cytosolic isoform, which has a high affinity for aldehydes.
Alternative Symbols: ALDC, ALDH-E1, ALDH1, ALDH11, MGC2318, PUMB1, RALDH1
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Molecular Weight
- 55kDa
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Gene ID
- 216
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NCBI Accession
- NP_000680
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UniProt
- P00352
Target
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