Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1) Peptide
Quick Overview for Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1) Peptide (ABIN8094384)
Target
Source
Application
-
-
Purpose
- ALDH4A1 Peptide
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Comment
-
This is a synthetic peptide designed for use in combination with anti-ALDH4A1 antibody ( ARP45697_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- ALDH4A1 (Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1))
-
Background
-
Background Information: ALDH4A1 belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline.This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Two transcript variants encoding the same protein have been identified for this gene.
Alternative Symbols: ALDH4, P5CD, P5CDh, P5CDhL, P5CDhS
-
Molecular Weight
- 62kDa
-
Gene ID
- 8659
-
NCBI Accession
- NP_003739
-
UniProt
- P30038
Target
-
