Aldo-keto Reductase Family 1 Member C4 (AKR1C4) (N-Term) Peptide
Quick Overview for Aldo-keto Reductase Family 1 Member C4 (AKR1C4) (N-Term) Peptide (ABIN8094397)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- AKR1C4 Peptide - N-terminal region
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Sequence
- MDPKYQRVEL NDGHFMPVLG FGTYAPPEVP RNRAVEVTKL AIEAGFRHID
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- AKR1C4 Antibody (ARP97778_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- AKR1C4 (Aldo-keto Reductase Family 1 Member C4 (AKR1C4))
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Background
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Background Information: This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the bioreduction of chlordecone, a toxic organochlorine pesticide, to chlordecone alcohol in liver. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alternative Symbols: C11, CDR, DD4, CHDR, DD-4, HAKRA, 3-alpha-HSD
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Molecular Weight
- 35 kDa
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Gene ID
- 1109
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NCBI Accession
- NP_001809
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UniProt
- P17516
Target
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