alpha-Methylacyl-CoA Racemase (AMACR) (C-Term) Peptide
Quick Overview for alpha-Methylacyl-CoA Racemase (AMACR) (C-Term) Peptide (ABIN8094470)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Purpose
- AMACR Peptide - C-terminal region
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Sequence
- IFDGTDACVT PVLTFEEVVH HDHNKERGSF ITSEEQDVSP RPAPLLLNTP
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-AMACR Antibody (ARP60806_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- AMACR (alpha-Methylacyl-CoA Racemase (AMACR))
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Background
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Background Information: This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene.
Alternative Symbols: CBAS4, RACE, RM, AMACRD
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Molecular Weight
- 42kDa
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Gene ID
- 23600
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NCBI Accession
- NP_055139
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UniProt
- Q9UHK6
Target
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