Amino-terminal Enhancer of Split (AES) (Middle Region) Peptide
Quick Overview for Amino-terminal Enhancer of Split (AES) (Middle Region) Peptide (ABIN8094514)
Target
Source
Application
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Protein Region
- Middle Region
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Purpose
- AES Peptide - middle region
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-AES antibody ( ARP32323_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- AES (Amino-terminal Enhancer of Split (AES))
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Background
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Background Information: AES is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes.The protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho, a protein involved in neurogenesis during embryonic development. The encoded protein, which belongs to the groucho/TLE family of proteins, can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms have been found for this gene.
Alternative Symbols: AES-1, AES-2, ESP1, GRG, GRG5, TLE5
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Molecular Weight
- 29kDa
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Gene ID
- 166
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NCBI Accession
- NP_945320
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UniProt
- Q14CJ1
Target
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