ATG5 Autophagy Related 5 (ATG5) (Middle Region) Peptide
Quick Overview for ATG5 Autophagy Related 5 (ATG5) (Middle Region) Peptide (ABIN8095141)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- ATG5 Peptide - middle region
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Sequence
- SQVINEMQKK DHKQLWMGLQ NDRFDQFWAI NRKLMEYPPE ENGFRYIPFR
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- ATG5 Antibody (ARP88991_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- ATG5 (ATG5 Autophagy Related 5 (ATG5))
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Background
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Background Information: The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Two transcript variants encoding different protein isoforms have been found for this gene.
Alternative Symbols: Apg5l, Atg5l, Paddy, C88337, AW319544, 2010107M05Rik, 3110067M24Rik
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Molecular Weight
- 30 kDa
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Gene ID
- 11793
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NCBI Accession
- NP_001300942
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UniProt
- Q99J83
Target
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