BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (Middle Region) Peptide
Quick Overview for BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L) (Middle Region) Peptide (ABIN8095488)
Target
Origin
Source
Application
-
-
Protein Region
- Middle Region
-
Purpose
- Bnip3l Peptide - middle region
-
Sequence
- CDSPSPQEDG QIMFDVEMHT SRDHSSQSEE EVVEGEKEVE ALKKSADWVS
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Comment
-
This is a synthetic peptide designed for use in combination with anti-Bnip3l Antibody (ARP58878_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
-
Background
-
Background Information: Bnip3l induces apoptosis. It interacts with viral and cellular anti-apoptosis proteins. It can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. It inhibits apoptosis induced by BNIP3. It is involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. Bnip3l may function as a tumor suppressor.
Alternative Symbols: C86132, D14Ertd719e, Nip3L, Nix
-
Molecular Weight
- 24kDa
-
Gene ID
- 12177
-
NCBI Accession
- NP_033891
-
UniProt
- Q9Z2F7
Target
-
