BH3 Interacting Domain Death Agonist (BID) (C-Term) Peptide
Quick Overview for BH3 Interacting Domain Death Agonist (BID) (C-Term) Peptide (ABIN8095547)
Target
Origin
Source
Application
-
-
Protein Region
- C-Term
-
Purpose
- BID Peptide - C-terminal region
-
Sequence
- LRNTSRSEED RNRDLATALE QLLQAYPRDM EKEKTMLVLA LLLAKKVASH
-
-
BH3 Interacting Domain Death Agonist (BID) peptide
BID Reactivity: Human Host: Synthetic BP, Imm
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Comment
-
This is a synthetic peptide designed for use in combination with anti-BID Antibody (ARP61037_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- BID (BH3 Interacting Domain Death Agonist (BID))
-
Background
-
Background Information: This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
Alternative Symbols: FP497, MGC15319, MGC42355
-
Molecular Weight
- 27kDa
-
Gene ID
- 637
-
NCBI Accession
- NP_932070
-
UniProt
- B3KT21
Target
-
