Cadherin 8 (CDH8) (C-Term) Peptide
Quick Overview for Cadherin 8 (CDH8) (C-Term) Peptide (ABIN8095896)
Target
Origin
Source
Application
-
-
Protein Region
- C-Term
-
Purpose
- CDH8 Peptide - C-terminal region
-
Sequence
- QIYGYEGRGS VAGSLSSLES TTSDSDQNFD YLSDWGPRFK RLGELYSVGE
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Comment
-
This is a synthetic peptide designed for use in combination with anti- CDH8 Antibody (ARP84819_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Buffer
- Lyophilized powder
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
-
-
- Cadherin 8 (CDH8)
-
Background
-
Background Information: This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.
Alternative Symbols: Nbla04261
-
Molecular Weight
- 87 kDa
-
Gene ID
- 1006
-
NCBI Accession
- NP_001787
-
UniProt
- P55286
Target
-
