Calreticulin (CALR) (Middle Region) Peptide
Quick Overview for Calreticulin (CALR) (Middle Region) Peptide (ABIN8096070)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- CALR Peptide - middle region
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Sequence
- ASKPEDWDER AKIDDPTDSK PEDWDKPEHI PDPDAKKPED WDEEMDGEWE
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Calreticulin (CALR) peptide (Ovalbumin)
CALR Reactivity: Human Host: Synthetic WB, Imm, SDS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-CALR Antibody(ARP58880_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Calreticulin (CALR)
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Background
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Background Information: Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is located in the endoplasmic and sarcoplasmic reticulum where it may bind calcium.
Alternative Symbols: CRT, FLJ26680, RO, SSA, cC1qR
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Molecular Weight
- 46kDa
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Gene ID
- 811
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NCBI Accession
- NP_004334
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UniProt
- P27797
Target
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