Cardiac Troponin T (cTnT) (N-Term) Peptide
Quick Overview for Cardiac Troponin T (cTnT) (N-Term) Peptide (ABIN8096265)
Target
Source
Application
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Protein Region
- N-Term
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Purpose
- TNNT2 Peptide - N-terminal region
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-TNNT2 antibody ( ARP41717_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))
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Background
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Background Information: TNNT2 is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in the gene encoding TNNT2 have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined.
Alternative Symbols: CMH2, CMPD2, MGC3889, TnTC, cTnT, RCM3, LVNC6
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Molecular Weight
- 35kDa
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Gene ID
- 7139
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NCBI Accession
- NP_000355
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UniProt
- A2TDB9
Target
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