Cathepsin K (CTSK) (Middle Region) Peptide
Quick Overview for Cathepsin K (CTSK) (Middle Region) Peptide (ABIN8096393)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- CTSK Peptide - middle region
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Sequence
- SPQNLVDCVS ENDGCGGGYM TNAFQYVQKN RGIDSEDAYP YVGQEESCMY
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Cathepsin K (CTSK) peptide
CTSK Reactivity: Human, Cow, Dog, Mouse, Rat, Pig Host: Synthetic BP, Imm
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-CTSK Antibody (ARP60949_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Cathepsin K (CTSK)
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Background
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Background Information: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
Alternative Symbols: CTS02, CTSO, CTSO1, CTSO2, MGC23107, PKND, PYCD
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Molecular Weight
- 37kDa
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Gene ID
- 1513
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NCBI Accession
- NP_000387
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UniProt
- P43235
Target
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