CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) Peptide
Quick Overview for CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB) Peptide (ABIN8096435)
Target
Source
Application
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Purpose
- CEBPB Peptide
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-CEBPB antibody ( ARP31259_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))
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Background
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Background Information: The protein encoded by this intronless gene, CEBPB, is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene.
Alternative Symbols: LAP, CRP2, TCF5, IL6DBP, NF-IL6, C/EBP-beta
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Molecular Weight
- 36kDa
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Gene ID
- 1051
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NCBI Accession
- NP_005185
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UniProt
- P17676
Target
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