CCAAT/enhancer Binding Protein (C/EBP), zeta (CEBPZ) (N-Term) Peptide
Quick Overview for CCAAT/enhancer Binding Protein (C/EBP), zeta (CEBPZ) (N-Term) Peptide (ABIN8096444)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- CEBPZ Antibody - N-terminal region
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Sequence
- MAAVKEPLEF HAKRPWRPEE AVEDPDEEDE DNTSEAENGF SLEEVLRLGG
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- CEBPZ Antibody (ARP38679_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- CEBPZ (CCAAT/enhancer Binding Protein (C/EBP), zeta (CEBPZ))
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Background
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Background Information: This gene belongs to the CEBP family. The encoded protein plays a role in cellular response to environmental stimuli through a transcriptional process that involves heat shock factors, conserved DNA elements (heat shock elements or HSEs) and CCAAT boxes. The protein acts as a DNA-binding transcriptional activator and regulates the heat-shock protein 70 (HSP70) promoter in a CCAAT-dependent manner. The protein is also involved in cell growth and differentiation, particularly, hematopoietic differentiation. Methylation of the promoter of this gene or mutations within the gene may be correlated with occurance of acute myeloid leukemia (AML).
Alternative Symbols: CBF, CBF2, NOC1, HSP-CBF
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Molecular Weight
- 115 kDa
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Gene ID
- 10153
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NCBI Accession
- NP_005751
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UniProt
- Q03701
Target
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