Chitotriosidase (CHIT1) (Middle Region) Peptide
Quick Overview for Chitotriosidase (CHIT1) (Middle Region) Peptide (ABIN8096904)
Target
Origin
Source
Application
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Protein Region
- Middle Region
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Purpose
- CHIT1 Peptide - middle region
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Sequence
- WEYPGSQGSP AVDKERFTTL VQDLANAFQQ EAQTSGKERL LLSAAVPAGQ
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- CHIT1 Antibody (ARP97587_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
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Background
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Background Information: Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.
Alternative Symbols: CHI3, CHIT, CHITD
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Molecular Weight
- 51 kDa
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Gene ID
- 1118
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NCBI Accession
- NP_001243054
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UniProt
- Q13231
Target
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